Etiology

  • Post-infectious, often Campylobacter

  • Post-vaccine (rare)

Pathogenesis

  • Autoimmune attack on peripheral myelin

  • Ascending demyelination

Clinical Features

  • Ascending weakness

  • Areflexia

  • Autonomic dysfunction

  • Possible respiratory failure

Treatment

  • IVIG or plasmapheresis

  • Supportive care

  • Monitor respiratory function