NEUROLOGY
Etiology
Idiopathic (most common)
Drug-induced (antipsychotics)
Genetic forms (LRRK2)
Pathogenesis
Loss of dopaminergic neurons in substantia nigra
Lewy bodies (α-synuclein)
Clinical Features
Resting tremor
Bradykinesia
Rigidity
Shuffling gait
Masked facies
Treatment
Levodopa/carbidopa
Dopamine agonists
MAO-B inhibitors
DBS in advanced cases