GASTROENTEROLOGY
Etiology
Multifactorial: gut-brain axis dysfunction
Stress, altered motility, visceral hypersensitivity
Pathogenesis
Dysregulated neural and hormonal signaling
Altered microbiome
Post-infectious changes
Diagnosis
Rome IV criteria
Exclude organic disease
Treatment
Diet (low FODMAP)
Antispasmodics
Laxatives or antidiarrheals
Psychological therapy (CBT)