NEPHROLOGY
Etiology
• Group A β-hemolytic Streptococcus infection (pharyngitis/skin)
Pathogenesis
• Immune complex deposition in glomeruli → complement activation → nephritis
Clinical features
• Hematuria (cola-colored urine)
• Oliguria, edema, hypertension
• Often occurs in children
Lab findings
• ↑ ASO titers, ↓ C3
• RBC casts in urine
• Mild proteinuria
Treatment
• Supportive: diuretics, antihypertensives
• Antibiotics for infection